Could something as common as a blister on your foot lead to serious health crisis? Model Gemma Downey noticed an oddly-colored blister on her ankle and she put a bandage over it. Soon after her ankle began to swell and she couldn’t walk on it. She was placed on antibiotics but it continued to get worse and her skin turned blue. Dr. Travis warns that if you have systemic symptoms you absolutely need to go to the ER.