The Doctors’ 2,500-Pound Weight Loss Special

Couple Loses Weight to Find Spark

Amy and Matthew say they had grown too comfortable together. Weighing in at a combined 822 pounds, the couple indulged in huge portions and fast-food meals. But when their weight threatened their future family plans, Matthew and Amy say they decided...

Birthday Gift Leads to 200-Pound Loss!

When Desiree was 19, she tore the ligaments in her knees in a workplace accident. At about the same time, her father was diagnosed with cancer. The 34-year-old makeup artist says the two traumatic events led her to soothe her stress and anxiety with...

Fitness Setback Drives Weight Loss

Mike, 26, says he was always a big kid, even bigger than his kindergarten teacher. As an adult, he filled up on 10,000 calories in an average day, which caused his weight to swell to 607 pounds. Hear how Mike dealt with an exercise setback. And, get...

Couple Reveals Surprise Addition

Amy and Matthew say they had grown too comfortable together. Weighing in at a combined 822 pounds, the couple indulged in huge portions and fast-food meals. After a dramatic weight loss transformation, the couple shares a special surprise!